CD44 antibody

Catalog No. ABIN1177309

This Mouse Monoclonal antibody specifically detects CD44 in FACS. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for CD44 antibody (ABIN1177309)

Target: CD44

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 515

Product Details anti-CD44 Antibody

Brand: BD Pharmingen™

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterility: 0.2 μm filtered

Endotoxin Level: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

References for anti-CD44 antibody (ABIN1177309)

Kansas, Muirhead, Dailey: "Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans." in: Blood, Vol. 76, Issue 12, pp. 2483-92, (1991) (PubMed).

Target Details for CD44

Target: CD44

Alternative Name: CD44 (Pgp-1, H-CAM, Ly24)

Background: Reacts with CD44, and 85 kDa glycoprotein that is expressed on leukocytes, erythrocytes, epithelial cells and weakly on platelets. CD44 is a member of the hyaladherin family of hyaluronan-binding proteins, with structural similarities to selectins. It has a functional role in cell migration, lymphocyte homing and adhesion during hematopoiesis and lymphocyte activation. 515 monoclonal antibody has been reported to be able to block cell adhesion to the hyaluronic acid. Flow cytometric analysis for CD44. Human peripheral blood lymphocytes were stained either with the Purified NA/LE Mouse Anti-Human CD44 antibody (solid line) or a Mouse IgG1 isotype control (dashed line) followed by a FITC Goat Anti-Mouse IgG/IgM polyclonal secondary antibody and analyzed on a BD FACScan™ instrument.
Synonyms: Pgp-1, H-CAM, Ly24

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling